A new medication, Jetrea (ocriplasmin), has been approved by the FDA for VMA (symptomatic vitreomacular adhesion), an eye condition related to aging that can lead to complications and vision loss. When the vitreous gel adheres too strongly to the retina, it can lead to VMT (vitreomacular traction), which may in the long-run affect vision significantly. The patient may eventually develop a range o
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Jetrea (Ocriplasmin) Approved For Symptomatic Vitreomacular Adhesion in the Eyes, FDA
Posted by Praveen (#2) 4253 days ago (Editorial)Diabetic Macular Edema Responds Best to Frequent Ranibizumab
Posted by Bharat (#1) 4202 days ago (Editorial)
Aggressive treatment with ranibizumab during year 3 may be more effective for diabetic macular edema (DME) than less-intensive treatment, according to 3-year outcomes from an ongoing randomized clinical trial published online October 8 in the Archives of Ophthalmology. Ranibizumab is a monoclonal antibody against vascular endothelial growth factor (VEGF), which promotes angiogenesis. The purpose
Mutation Disrupts Architecture Of Rod Sensory Cilium
Posted by Praveen (#2) 4177 days ago (Editorial)
Using a new technique called cryo-electron tomography, two research teams at Baylor College of Medicine have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.To s
Epigenetic Study Suggests Immune System Could Play A Central Role In AMD
Posted by Praveen (#2) 4087 days ago (Editorial)
Changes in how genes in the immune system function may result in age-related macular degeneration (AMD), the leading cause of visual impairment in older adults, based on preliminary research conducted by National Institutes of Health (NIH) investigators. The study identified decreased levels of DNA methylation, a chemical reaction that switches off genes, on the interleukin-17 receptor C gene (I
Insulin plus Growth Factor Inhibitor Limits Vision Damage In Diabetic Mice
Posted by Praveen (#2) 4077 days ago (Editorial)
A new therapeutic approach to diabetes that combines insulin and an inhibitor of the epidermal growth factor (EGF) betacellulin could limit the progression of diabetic macular edema (DME), Cleveland Clinic researcher Bela Anand-Apte, MD, PhD, said at the American Society for Cell Biology Annual Meeting, on Dec. 17 in San Francisco. The study, conducted with insulin-dependent diabetic mice, showe
App Expands Screening for Diabetic Retinopathy
Posted by Praveen (#2) 4029 days ago (Editorial)
An app-based telemedicine program significantly increases screening for diabetic retinopathy at community health clinics, according to a multicenter randomized controlled trial. This is a more convenient form of screening than traditional surveillance by an ophthalmologist, and it is "done right in the clinic," Steven Mansberger, MD, director of glaucoma services at the Devers Eye Institute in Po
First Drug to Help Melanoma of the Eye
Posted by Praveen (#2) 4022 days ago (Editorial)
AstraZeneca's experimental drug, selumetinib, is the first targeted medication to show a significant clinical benefit for patients with melanoma of the eye (metastatic uveal melanoma), researchers from the Memorial Sloan-Kettering Cancer Center explained at the 49th annual meeting of the American Society of Clinical Oncology (ASCO), in Chicago, Illinois.
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Age-Related Macular Degeneration and Genes: Scientists Identify 7 New Genetic Risk Factors
Posted by Praveen (#2) 4009 days ago (Editorial)
New research from government scientists paints a clearer picture of how genetics may play a role in age-related macular degeneration, or AMD, the leading cause of blindness in people age 60 and older. Researchers have identified seven places on the human genome that seem to be linked with the vision loss condition, adding to the 12 that had been identified in previous research. The study is publi