Leptin - commonly dubbed the "fat hormone" - does more than tell the brain when to eat. A new study by researchers at The University of Akron and Northeast Ohio Medical University (NEOMED) shows that leptin may play a role in hearing and vision loss. This discovery, made in zebrafish treated to produce low leptin, could ultimately help doctors better understand sensory loss in humans. While the s
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Leptin Implicated in Hearing and Vision Loss
Posted by Praveen (#2) 4282 days ago (Editorial)Natural Defense against Infection Discovered in The Cornea
Posted by Praveen (#2) 4283 days ago (Editorial)
Exposed tissue surfaces, including skin and mucous membranes, are under constant threat of attack by microorganisms in the environment. The layer of cells that line these areas, known as epithelial cells, are the first line of defense against these pathogens, but the underlying molecular mechanisms that allow them to repel microbes are unknown. In this issue of the Journal of Clinical Investigat
Fat Hormone May Play Role in Hearing, Vision Loss
Posted by Praveen (#2) 4283 days ago (Editorial)
Leptin commonly dubbed the "fat hormone" does more than tell the brain when to eat. A new study by researchers at The University of Akron and Northeast Ohio Medical University. (NEOMED) shows that leptin may play a role in hearing and vision loss. This discovery, made in zebrafish treated to produce low leptin, could ultimately help doctors better understand sensory loss in humans.To see more det
Glaucoma, A Stealth Disease And Major Cause of Blindness
Posted by Praveen (#2) 4283 days ago (Editorial)
Glaucoma is a major cause of blindness around the world, but especially in developing countries. The World Health Organization says glaucoma is a greater public health challenge than cataracts, because the blindness caused by glaucoma is permanent. If you think you are not at risk for glaucoma, think again. Glaucoma is a disease that steals the sight of people around the world, and they typical
Fewer Ranibizumab Injections, Same Visual Acuity in AMD
Posted by Praveen (#2) 4283 days ago (Editorial)
Patients with neovascular age-related macular degeneration (nAMD) who receive intravitreal ranibizumab injections on an individualized schedule have the same visual acuity gains as patients treated on a standard monthly schedule, and individualized plans reduce the number of office visits and injections, according to a single-institution phase 4 study. Irmela Mantel, MD, from the Ophthalmology De
Cholesterol-Lowering Drugs May Be Linked to Increased Cataract Risk
Posted by Praveen (#2) 4290 days ago (Editorial)
Patients using cholesterol-lowering statin drugs may be at increased risk of developing age-related cataracts, according to a study. Statins and Diabetes Both Increase Cataract Risk The study included nearly 6,400 patients seen at the optometry clinic at the University of Waterloo in 2007-08. Of these, 452 patients had type 2 diabetes. Statin treatment and diabetes were evaluated as possible risk
Antioxidant May Prevent, Even Cure, Cataracts and other degeneration Eye Disorders
Posted by Praveen (#2) 4290 days ago (Editorial)
Researchers at Missouri University of Science and Technology are studying eye drops prepared with the antioxidant N-acetylcysteine amide (NACA) as a treatment for these eye conditions. NACA is an improvement over another experimental treatment, theantioxidant N-acetylcysteine (NAC), because it passes more easily across cell membranes, allowing the medication to be used in lower doses. NACA is al
Aflibercept Improves Visual Acuity in Patients With CRVO
Posted by Praveen (#2) 4290 days ago (Editorial)
Patients with central retinal vein occlusion (CRVO) who received aflibercept achieved significant improvement in visual acuity, compared with those receiving sham treatment in 2 phase 3 clinical trials. Researchers presented the trial results at the 12th European Society of Retina Specialists (EURETINA) Congress in Milan, Italy. Last week, on the basis of these 2 trials, the US Food and Drug Admi